OUR RESEARCH

Our lab is interested in identifying molecular interactions involving the dopamine system. Dopamine signalling has a role in a variety of neurological processes including the reward, motor and cognitive systems.  Not surprisingly there are a variety of diseases that implicate the dopamine system including drug addiction, schizophrenia and Parkinson’s disease. Key components of the dopamine system include dopamine receptors and the dopamine transporter. We are interested in identifying mechanisms that regulate the activity of dopamine receptors and transporter. One mechanism by which dopaminergic proteins can be regulated is through protein-protein interactions. Our laboratory has interests in identifying and elucidating the mechanisms that govern dopaminergic protein-protein interactions and examining the role of these interactions in the molecular pathophysiology of diseases.

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Currently, we have 2 main projects in the lab:

(1) Identification of interactions involving the dopamine D2 receptor.

(2) Identification of interactions involving the dopamine transporter.

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