PUBLISHED WORK

RECENT PUBLICATIONS

Han, J., Luk, B. and LEE, F.J.S (2017) Neuroprotective effects of extracellular DJ-1 on reperfusion injury in SH-SY5Y cells. Synapse 71:e21963.

Khakshour S, Labrecque MP, Esmaeilsabzali H, LEE F.J.S., Cox ME, Park EJ, Beischlag TV.(2017) Retinoblastoma protein (Rb) links hypoxia to altered mechanical properties in cancer cells as measured by an optical tweezer. Sci Rep. 7(1):7833.

Labrecque MP, Takhar MK, Nason R, Santacruz S, Tam KJ, Massah S, Haegert A, Bell RH, Altamirano-Dimas M, Collins CC, LEE FJS, Prefontaine GG, Cox ME, Beischlag TV. (2016). The retinoblastoma protein regulates HIF1-mediated genetic programs, tumor cell invasiveness and neuroendocrine differentiation in prostate cancer cells. Oncotarget. 7(17): 24284-302.

Luk, B., Mohammed, M, Liu, F and LEE, F.J.S (2015) A Physical Interaction between the Dopamine Transporter and DJ-1 Facilitates Increased Dopamine Reuptake. PLOS One DOI: 10.1371/ journal.pone.0136641

Khan, S and LEE, F.J.S (2014) Delineation of domains within CB1 and D2R that mediate the formation of the heterodimer CB1-D2R complex. J Mol. Neurosci 53(1):10-21.

SELECT PUBLICATIONS

Wang, M., Li, S., Zhang, H., Pei, L., Zuo, S., Lee, F.J.S., Wang , Y.T. and Liu, F (2012) Direct interaction between GluR2 and GAPDH regulates AMPAR-mediated excitotoxicity. Mol Brain. 5: 13

Nai, Q., Li, S., Wang, S-H, Liu, J., Lee, F.J.S., Frankland, P. W. and Liu, F. (2010) Uncoupling the D1-NMDA receptor complex impairs NMDA-dependent LTP and working memory. Biological Psychiatry 67:246-54.

Saab,B.J., Georgiou, J., Nath, A., Lee, F.J.S., Wang, M., Michalon, A., Liu, F., Mansuy, I.M. and Roder, J.C. (2009) Exploration, Synaptic Plasticity,and Rapid Acquisition of Spatial Memory. Neuron 63: 643-56.

Lee, F. J. S., Pei, L. and Liu, F. (2009) Disruption of the dopamine transporter-dopamine D2 receptor interaction in schizophrenia. Synapse 63:710-2.

Wang, H., Wu, L-J, Kim, S. S., Lee, F.J.S., Gong, B., Toyoda, H., Ren, M., Xu, H., Liu, F., Zhao, M-G and Zhuo, M. (2008) FMRP acts as a key messenger for dopamine modulation in the forebrain. Neuron 59: 634-7.

Lee, F. J. S. and Liu, F. (2008) Genetic factors involved in the pathogenesis of Parkinson’s disease. Brain Res Rev 58: 354-64.

Lee, F. J. S., Pei, L., Moszczynska, A., Vukusic, B., Fletcher, P. J. and Liu, F. (2007) Dopamine transporter cell surface localization facilitated by a direct interaction with the dopamine D2 receptor. EMBO J 26: 2127-37.

Zou, S., Li, L., Pei,L., Vukusic, B., Van Tol, H. H. M., Lee, F. J. S., Wan, Q. and Liu, F. (2005) Protein-protein coupling/uncoupling enables dopamine D2 receptor regulation of AMPA receptor-mediated excitotoxicity. J. Neurosci 25(17):4385-95.

Lee, F. J. S. and Liu, F. (2004) Direct interactions between NMDA and D1 receptors: A tale of tails. Biochem. Soc. Trans. 32(6):1032-6.

Pei, L., Lee, F. J. S., Moszczynska, A., Vukusic, B. and Liu, F. (2004) Regulation of dopamine D1 receptor function by physical interaction with the NMDA receptors. J. Neurosci 24(5):1149-58.

Lee, F. J. S., Xue, S., Pei, L., Vukusic, B., Chéry, N., Wang, Y., Wang, Y. T., Niznik, H. B., Yu, X.-M. and Liu, F. (2002) Dual regulation of NMDA receptor functions by direct protein-protein interactions with the dopamine D1 receptor. Cell 111(2):219-30.

Xu, J., Kao, S.-Y., Lee, F. J. S., Song, W., Jin, L.-W. and Yankner B. A. (2002) Dopamine-dependent neurotoxicity of a-synuclein: A mechanism for selective neurodegeneration in Parkinson disease. Nat. Med. 8(6): 600-6.

Lee, F. J. S., Liu, F., Pristupa, Z. B., and Niznik H. B. (2001) Direct binding and functional coupling of a-synuclein to the dopamine transporter accelerates dopamine-induced apoptosis. FASEB J. 15(6):916-926.